Investigation of the relationship between air quality and health outcomes in Bilecik, Türkiye: A descriptive ecological study

Authors

  • Mehtap Yücel Necmettin Erbakan University image/svg+xml
  • Hasan Küçükkendirci Necmettin Erbakan University

DOI:

https://doi.org/10.37609/srinmed.70

Keywords:

air pollution, PM₂.₅, respiratory diseases, cardiovascular admissions, ecological study

Abstract

Objective: To evaluate temporal trends in air quality indicators and their ecological-level associations with respiratory and cardiovascular hospital admissions in two districts of Bilecik Province between 2020 and 2024.

Methods: This ecological, retrospective study used annual district-level data from two public hospitals and two fixed air-monitoring stations in Bilecik city center and Bozüyük. Annual mean concentrations of PM₁₀, PM₂.₅, SO₂, NO₂, O₃ and CO were obtained from routine monitoring records. Hospital admissions were classified using ICD-10 codes for major respiratory and cardiovascular conditions. Descriptive trends were examined, and ecological co-variation between pollutants and total respiratory/cardiovascular admissions was assessed using Spearman’s rank correlation (p<0.05).

Results: PM₁₀ levels declined in both districts, whereas PM₂.₅ concentrations increased and remained higher in Bozüyük. Respiratory and cardiovascular admissions decreased in 2020–2021 and rose again from 2022 onwards. At the district–year level, respiratory admissions were positively correlated with PM₂.₅ in Bozüyük and negatively correlated in the city center, while NO₂ showed negative correlations in both districts. Cardiovascular admissions were positively correlated with PM₂.₅ and temperature, whereas PM₁₀ showed a negative association, particularly in Bozüyük.

Conclusion: Air quality indicators and hospital admissions displayed distinct temporal and spatial patterns across the two districts, with a stronger PM₂.₅ burden and clearer ecological associations in Bozüyük, the more industrialized and traffic-intense district. Although not implying individual-level causality, the findings provide policy-relevant evidence supporting prioritization of PM₂.₅-focused monitoring, emission-control measures, and integration of environmental indicators into local health-surveillance systems in medium-sized industrial regions.

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References

World Health Organization. (2021). Ambient (outdoor) air pollution. Retrieved from: https://www.who.int/news-room/fact-sheets/detail/ambient-(outdoor)-air-quality-and-health Access date: 14.07.2025

GBD 2023 Risk Factors Collaborators. (2023). Global burden of disease 2023: Ambient air pollution. The Lancet, 401(10378), 198-245.

Cohen AJ, Brauer M, Burnett R, Anderson HR, Frostad J, Estep K, et al. (2017). Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015. The lancet, 389(10082), 1907-1918.

Thurston GD, Burnett RT, Turner MC, Shi Y, Krewski D, Lall R, et al. Ischemic heart disease mortality and long-term exposure to source-related components of US fine particle air pollution. Environmental health perspectives, 2016;124(6):785-794. doi: 10.1289/ehp.1509777

Gupta A, Singh A, Tarimci B, Sindhu AK, Bathvar P, Bedi S, Wint Yee Theik N, Shah V, Malhotra S, Khealani M, Usha Jeevani Obulareddy S, Kukreja G, Kanitkar A. PM2.5 and risk of lung cancer and as-sociated mortality: An umbrella meta-analysis. J Clin Oncol, 2024;42(16):e20012-e20012. doi: 10.1200/JCO.2024.42.16_suppl.e20012

Chen CY, Huang KY, Chen CC, Chang YH, Li HJ, Wang TH, Yang PC. The role of PM2.5 exposure in lung cancer: mechanisms, genetic factors, and clinical implications. EMBO Mol Med. 2025;17(1):31-40. doi: 10.1038/s44321-024-00175-2

Mustafic H, Jabre P, Caussin C, Murad MH, Escolano S, Tafflet M, Périer MC, Marijon E, Vernerey D, Empana JP, Jouven X. Main air pollutants and myocardial infarction: a systematic review and meta-analysis. JAMA. 2012;307(7):713-21. doi:10.1001/jama.2012.126

Prabhakaran D, Mandal S, Krishna B, Magsumbol M, Singh K, Tandon N, Narayan KMV, Shivashankar R, Kondal D, Ali MK, Srinath Reddy K, Schwartz JD; GeoHealth Hub Study investigators, COE-CARRS Study investigators. Exposure to Particulate Matter Is Associated With Elevated Blood Pressure and In-cident Hypertension in Urban India. Hypertension. 2020;76(4):1289-1298. doi: 10.1161/HYPERTENSIONAHA.120.15373

European Environment Agency. (2024). Air pollution Retrieved from: https://www.eea.europa.eu/en/topics/in-depth/air-pollution RtCAP (Right to Clean Air Platform). (2024). Dark Report 2024; Air Pollution and Health Effects.

Turkish Statistical Institute (TUİK). (2024). Address-Based Population Registration System Results-2024. Retrieved from: https://data.tuik.gov.tr/Bulten/Index?p=Adrese-Dayali-Nufus-Kayit-Sistemi-Sonuclari-2024-53783

Kotan B, Erener A. Spatial and Temporal Variation of Main Air Pollutants and Their Concentrations in Relation to Meteorological Conditions in the Industrialized City of Kocaeli. Journal of Geography, 2023;(46):19-29. doi: 10.26650/jgeog2023-1158583

Aydın O, Raja NB. Spatial-Temporal Analysis of Particulate Matter (PM10) and Sulphur Dioxide (SO2) Concentrations in Ankara Using Climate Parameters. Journal of Natural Hazards and Environment, 2025;11(1):249-267.

IQAir. (2024). World Air Quality Report 2023. Retrieved from: https://www.iqair.com/world-most-polluted-countries

Pope III CA, Coleman N, Pond ZA, Burnett RT. Fine particulate air pollution and human mortality: 25+ years of cohort studies. Environmental research, 2020;183:108924. doi: 10.1016/j.envres.2019.108924

Kyung SY, Jeong SH. Particulate-matter related respiratory diseases. Tuberculosis and respiratory dis-eases, 2020;83(2):116-121. doi: 10.4046/trd.2019.0025

Çapraz Ö, Deniz A. Assessment of hospitalizations from asthma, chronic obstructive pulmonary dis-ease and acute bronchitis in relation to air pollution in İstanbul, Turkey. Sustainable Cities and Socie-ty, 2021;72:103040. doi: 10.1016/j.scs.2021.103040

Shah AS, Langrish JP, Nair H, McAllister DA, Hunter AL, Donaldson K, et al. Global association of air pollution and heart failure: a systematic review and meta-analysis. The Lancet, 2013;382(9897):1039-1048. doi: 10.1016/ S0140-6736(13)60898-3

Brook RD, Rajagopalan S, Pope III CA, Brook JR, Bhatnagar A, Diez-Roux AV, et al. Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American Heart Association. Circulation, 2010;121(21):2331-2378. doi: 10.1161/CIR.0b013e3181dbece1

Lee H, Yoon HY. Impact of ambient temperature on respiratory disease: a case-crossover study in Seoul. Respiratory Research, 2024;25(1):73. doi: 10.1186/s12931-024-02699-0.

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Published

2026-04-26

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Research Articles

How to Cite

1.
Investigation of the relationship between air quality and health outcomes in Bilecik, Türkiye: A descriptive ecological study. SRINMED [Internet]. 2026 Apr. 26 [cited 2026 Apr. 27];3(1):30-8. Available from: https://srinmed.akademisyen.net/index.php/srinmed/article/view/70